Polarization and Repolarization of Macrophages
نویسندگان
چکیده
منابع مشابه
Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages.
Macrophages are innate immune cells that adopt diverse activation states in response to their microenvironment. Editing macrophage activation to dampen inflammatory diseases by promoting the repolarization of inflammatory (M1) macrophages to anti-inflammatory (M2) macrophages is of high interest. Here, we find that mouse and human M1 macrophages fail to convert into M2 cells upon IL-4 exposure ...
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We propose a type of lossless nonlinear polarizer, novel to our knowledge, a device that transforms any input state of polarization (SOP) of a signal beam into one and the same well-defined SOP toward the output, and perform this without any polarization-dependent losses. At the polarizer output end, the signal SOP appears to be locked to the input pump SOP. The polarizer is based on the nonlin...
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Monocytes originate from progenitor cells in the bone marrow and traffic via the bloodstream to peripheral tissues. During both homeostasis and in responses to clear pathogens, circulating monocytes leave the bloodstream and migrate into tissues where they, following exposure to local growth factors, pro-inflammatory cytokines and microbial products, differentiate into macrophage or dendritic c...
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Background: Macrophage polarization plays a critical role in determining the inflammatory states. Hepcidin is a key negative regulator of iron homeostasis and functions. Although hepcidin has been shown to affect ferroportin expression in macrophages, whether it affects macrophage polarization is still largely unknown. Objective: To address whether hepcidin ind...
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ژورنال
عنوان ژورنال: Journal of Clinical and Cellular Immunology
سال: 2015
ISSN: 2155-9899
DOI: 10.4172/2155-9899.1000319